Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin.

From synthetic functionalized analogues of vanchrobactin, a siderophore produced by the fish pathogenic bacteria Vibrio anguillarum serotype O2, several vanchrobactin analogues-norfloxacin conjugates were obtained and their antimicrobial activities against the wild-type and mutant strains of Vibrio anguillarum serotype O2 have been determined.

Autor: 
Souto A, Montaos MA, Balado M, Osorio CR, Rodríguez J, Lemos ML, Jiménez C.
Referencia: 
Bioorg Med Chem.
Volumen: 
21(1)
Pagina Inicial: 
295
Pagina final: 
302